150 years after Darwin

Author : Wahid Ahmad

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Jean-Baptiste Lamarck, predating Charles Darwin, proposed an early theory of evolution. He suggested that organisms could acquire traits during their lifetime in response to the environment, and these acquired traits could be inherited by their offspring. For example, in a population of giraffes with short necks, continuous neck stretching to reach leaves on tall trees could lead to longer necks over generations. However, modern genetics has revealed that traits acquired during an individual's life are not typically passed on through genetic material. Lamarck's theory, while influential, lacked empirical support and was eventually replaced by Darwin's theory of natural selection.

This theory was revised by Charles Darwin. Darwin's theory of evolution, a groundbreaking concept in the field of biology, introduced the idea that the all diversity of life can be traced to a common ancestor, through a process called natural selection. The core principles of Darwin's theory include variation within populations, competition for limited resources, and the differential survival and reproduction of individuals with advantageous traits. Let's explore an example featuring a population of rabbits in a meadow.

Consider a population of rabbits with variations in fur color. Some rabbits are brown, while others are lighter in color.

The meadow has various predators, including birds of prey. The brown fur provides better camouflage in the grassy environment, making it harder for predators to spot those rabbits.

Over time, the brown-furred rabbits are more likely to survive because they can hide more effectively from predators. They have a better chance of reaching reproductive age and having offspring.

The advantageous trait of brown fur is passed on to the next generation.

As generations go by, the majority of the rabbit population becomes brown, as this trait offers a survival advantage in the meadow. This change in fur color is an evolutionary adaptation driven by natural selection.

Charles Darwin conceived of evolution by natural selection without knowing that genes exist. Now mainstream evolutionary theory has come to focus almost exclusively on genetic inheritance and processes that change gene frequencies.

Back in the 1930s and 1940s, scientists came up with the main ideas of how evolution works. They mixed concepts like natural selection and genetics to create what's known as the modern synthesis. New variants of traits called alleles are created through random genetic changes call mutations in the DNA. Natural selection will determine the suitability of the variants which in turn will determine the frequency of alleles as they are passed down to future generation. Mathematics is used to explain how the frequency of different alleles or variants in a group of living things changes over time. Evolution is simply defined as changes in allele frequencies.

Since 1960’s, evolutionary biology has added some new ideas, but it mostly sticks to the same basics from the modern synthesis. This view, called the Standard Evolutionary theory.

However, this gene-centric perspective overlooks crucial aspects of evolution. The Extended Evolutionary Synthesis argues that other processes play significant roles in directing evolution. These include how an organism's physical development influences variation called developmental bias, how the environment directly affects traits called plasticity, how organisms modify their environments called niche construction, and how traits more than genes are transmitted across generations called extra-genetic inheritance.

The concept of developmental bias helps us understand how organisms adapt to their environments and evolve into different species. Take, for instance, cichlid fishes in Lake Malawi. Although they are more closely related to other cichlids in the same lake than those in Lake Tanganyika, both lakes' cichlids share remarkably similar body shapes.

Rather than attributing these similarities to coincidences through convergent evolution, where similar traits emerge due to similar environmental pressures, a more concise explanation involves the interplay of developmental bias and natural selection.

One key developmental bias in human evolution is related to the development of the neocortex, the outer layer of the brain responsible for higher cognitive functions. The neocortex has undergone considerable expansion in humans compared to other primates. This expansion is not solely due to the emergence of entirely new genes but also involves the repurposing and modification of existing genetic and developmental pathways.

The genes involved in regulating the size and complexity of the neocortex are ancient and conserved across many species. However, the specific ways these genes are activated, the timing of their expression, and the interactions with other genes and environmental factors during development play a crucial role in determining the unique features of the human brain.

The process of brain development in humans is biased by pre-existing developmental constraints, which means that certain trajectories are more likely to be followed due to the inherent properties of the developmental system. The complexity and size of the human brain, with its specific cognitive abilities, can be seen as an outcome of these biased developmental processes.

This idea helps explain how organisms adapt to their environments and diversify into various species. It suggests that rather than being entirely random, natural selection is guided along specific routes opened up by developmental processes, working in tandem with selection.

Genes are not the only factors involved in passing traits from one generation to the next. The Extended Evolutionary Synthesis suggests that other processes, like plasticity, play a crucial role. Plasticity refers to how living things can change their shape or form in response to their environment. While the Standard Evolutionary Theory sees this as minor adjustments or even random changes, the Extended Evolutionary Synthesis views plasticity as the initial step in adaptive evolution.

Plasticity allows organisms not only to survive in new environments but also to develop traits that are well-suited to those conditions. Traits can precede genes in adaptation, meaning that the trait comes first, and the genes supporting it follow in later generations. Studies of fish, birds, amphibians, and insects suggest that adaptations induced by the environment can lead to the colonization of new areas and the formation of new species.

This theory treats environment as a background condition that triggers or modifies selection but is not an active part of the evolutionary process. It doesn't distinguish between how organisms adapt to different situations, such as termites building mounds or responding to volcanic eruptions. In contrast, the EES sees these cases as fundamentally different.

Volcanic eruptions are unpredictable events unrelated to organisms' actions, while organisms like termites actively construct and regulate their homes in a consistent manner shaped by past experiences and influencing future ones. This concept, known as "niche construction," suggests that organisms play a role in directing their own evolution by systematically changing environments and biasing selection. In simpler terms, living things are not just reacting to their surroundings; they are actively shaping their evolution.Top of Form

 

Beyond just genes, there's a way living things pass on traits, and it's not just about parents giving their kids genes. The Extended Evolutionary Synthesis acknowledges that parents also pass on things from their own experiences, like the environment they grew up in. This broader idea is called 'extra-genetic inheritance.'

Extra-genetic inheritance includes passing on chemical marks on DNA, called epigenetic marks,that can influence things like fertility and disease resistance in different species. It also includes behaviors in animals that are learned and passed on socially, like chimpanzees cracking nuts or fish following migration patterns. Additionally, it involves the things living things create or change in their environment, such as beavers building dams or worms altering the soil they live in. Over the past decade, research has shown that this kind of inheritance is widespread and should be part of our general understanding of how traits are passed down.

When scientists use mathematical models to study how evolution works and include this extra-genetic inheritance, they get different predictions compared to models that only consider genes. These inclusive models help explain puzzling things in nature, like how certain birds quickly colonized North America or how plants with low genetic diversity can adapt. It even sheds light on how new species and ecosystems evolve over millions of years, with evidence suggesting that certain organisms, like sponges, have played a big role in creating opportunities for other life forms. So, it's not just about genes; it's about the broader impact of living things on their environment and how that shapes the future of life on Earth.Top of Form

The above insights derive from different fields, but fit together with surprising coherence. They show that variation is not random, that there is more to inheritance than genes, and that there are multiple routes to the fit between organisms and environments. Importantly, they demonstrate that development is a direct cause of why and how adaptation and speciation occur, and of the rates and patterns of evolutionary change.

SET consistently frames these phenomena in a way that undermines their significance. For instance, developmental bias is generally taken to impose ‘constraints’ on what selection can achieve — a hindrance that explains only the absence of adaptation. By contrast, the EES recognizes developmental processes as a creative element, demarcating which forms and features evolve, and hence accounting for why organisms possess the characters that they do.

 

Researchers in fields from physiology and ecology to anthropology are running up against the limiting assumptions of the standard evolutionary framework without realizing that others are doing the same. We believe that a plurality of perspectives in science encourages development of alternative hypotheses, and stimulates empirical work. No longer a protest movement, the EES is now a credible framework inspiring useful work by bringing diverse researchers under one theoretical roof to effect conceptual change in evolutionary biology.

 

Not at all

Charles Darwin's last book, published in 1881, focused on earthworms because they showcased an interesting cycle: the worms modified their environment and were adapted to thrive in it. Darwin's genius lay in drawing insights from various fields, shaping evolutionary thinking that emphasized evidence and synthesis from diverse areas.

 

Some argue that concepts like niche construction and phenotypic plasticity, highlighted in the 'extended evolutionary synthesis,' are not novel but have long been integral to evolutionary biology. These ideas are firmly established in the field and don't necessitate a distinct label. Their current prominence results from their proven explanatory power, not a lack of attention. Evolutionary biology continually explores various topics, including epistasis, cryptic genetic variation, extinction, climate change adaptation, and behavioral evolution, expanding the field's scope.

Contrary to portraying evolutionary theory as static, the discipline is dynamic, creative, and rapidly growing. Evolutionary biologists actively engage with diverse fields such as genomics, medicine, ecology, artificial intelligence, and robotics. Far from resisting new ideas, the field remains vibrant, inclusive, and progressive—an affirmation of ongoing evolution in evolutionary biology.

The focus on genes in evolutionary theory is crucial, as genetic changes strongly predict adaptation and speciation. Many adaptations, like antibiotic resistance and camouflage coloration, are directly tied to genetic alterations. While non-genetic processes, such as phenotypic plasticity, contribute to adaptability, the primary driver of evolutionary change is heritable differences in traits offering a selective advantage. The roles of plasticity, developmental bias, and epigenetic modification in adaptive traits lack robust evidence, necessitating further research. These factors, alongside niche construction and inclusive inheritance, influence evolutionary change but are not essential for evolution.

The call is for a broader perspective rather than divisions. Strengthening evidence for phenomena like phenotypic plasticity, inclusive inheritance, niche construction, and developmental bias is the most effective way to elevate their importance in evolutionary theory. Darwin's emphasis on rigorous evidence before making significant claims underscores the importance of robust research in the field of evolutionary biology.

 

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